| DryLab® |
| For information or support for DryLab, e-mail us or call +49 30 421559-0. Learn how DryLab® chromatography modeling software will improve the efficiency and quality of your method development efforts, save you time and money, and enhance your understanding of the chromatographic process.
Let DryLab® handle it for you... We all know that the "small stuff" is what makes or breaks a chromatography method. The trick is to keep the small stuff under control. DryLab models chromatography variables in seconds, and that power lets you evaluate a much wider range of experimental conditions than would ever be practical in the laboratory. With DryLab, you can quickly determine the effects of pH, temperature, buffer concentration, and more on your separation. Take a look at just some of the features DryLab has to offer. This systematic approach to computerized method optimization has many advantages:
With a minimum of experimental effort, DryLab provides you with maximum of information on your method. DryLab Q&A Q1: I work with difficult samples... will DryLab help me?" A1: DryLab includes LC modeling options for gradient conditions, isocratic %B, pH, ternary mobile phases, ionic strength, additive/buffer concentration, normal phase, temperature, reversed-phase gradient/temperature, as well as temperature program for GC separations (see figure below). In addition, DryLab's Column Optimization option lets you model changes to column dimensions, particle size, and flow rate. Dwell volume changes and peak tailing can also be modeled to simplify method transfer.  Click image to zoom Model all relevant variables for LC and GC separations! Q2: Can I model more than one variable at a time?" A2: DryLab's 3D Resolution Map predicts optimum mobile phase conditions for modes that model two variables simultaneously (see figure below). Modeling gradient conditions and temperature, for example, provides excellent selectivity control for complex samples. See a demonstration of the new 3D resolution “Design Space.”  Click image to zoom Use the 3D Resolution Map to Model Two Separation Variables Simultaneously Q3: I am only interested in one degradation product in a complex mixture. Will DryLab help? A3: DryLab's Resolution Map shows how resolution changes with separation conditions — for one peak, for several peaks, or for all peaks under evaluation (see figure below).  Click image to zoom Find the Best Conditions for ANY Component in a Complex Mixture Q4: Will a change in separation conditions make my method work again? A4: DryLab tells you at a glance by modeling and comparing a separation under a variety of conditions (see figure below).  Click image to zoom Troubleshoot Existing Methods Q5: Can DryLab be applied to training? A5: Training new staff is time-consuming, and mistakes made at the instrument can be costly. DryLab lets novices do their learning on the computer. As they alter experimental conditions, DryLab provides immediate feedback. And, DryLab comes with a Tutorial Guide and built-in examples for self-instruction. Teach New Chromatographers Q6: I need to shorten my run time to get more samples done each day. Is DryLab useful for this? A6: DryLab lets you try out different column configurations and flow rates in seconds. Shorten Run Times! Q7: How sensitive is my method to small inaccuracies in conditions? A7: The DryLab-3-Dimensional Resolution Space shows you EXACTLY how robust your method is (see figure below). Identify the best conditions to avoid reproducibility problems. have the best separation.  Evaluate Method Robustness Q8: How easy is it to enter my data into DryLab? A8: DryLab imports data files from nearly any chromatography data system or allows you to customize an import template. Import Your Data Files! Q9: My separations almost always have tailing peaks. A9: DryLab models peak tailing to give you a realistic prediction of what your separation will look like when you run your DryLab conditions in the laboratory (see figure below).  Click image to zoom Account for Peak Tailing in Your Modeling! Q10: Can DryLab be used to help standardize gradient methods for a variety of intruments in our lab? A10: DryLab's Gradient Editor predicts the optimum linear gradient for your separation and lets you model multisegmented gradients or adjust methods for different instrument configurations. For example, you can adjust a method for an instrument with a different dwell volume (see figure below).  Click image to zoom Transfer Gradient Methods from One Instrument to Another! |
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