Let DryLab® handle it for you...

We all know that the "small stuff" is what makes or breaks a chromatography method. The trick is to keep the small stuff under control. DryLab^® models chromatography variables in seconds - and that power lets you evaluate a much wider range of experimental conditions than would ever be practical in the laboratory. With DryLab^®, you can quickly determine the effects of pH, temperature, buffer concentration and more on your separation.

Take a look at just some of the features DryLab^® has to offer. The systematic computerized method optimization has many advantages:

• DryLab^® saves you a great deal of time: Either when you are optimizing your method - most experiments can be simulated in a matter of seconds – or when you are running your method on a routine base- the optimization process then allows you to minimize retention and run times.
  
  
• DryLab^® eases the exchange of a method from one instrument to another. For example via email DryLab- files can be transferred to different locations. The model then can be adjusted to fix parameters of other instruments (e.g. with differing dwell volumes) without loosing quality or the control of the method.
  
  
• DryLab^® shows you which parameters are more sensitive then others and where adjustments can be made without loosing quality.
  
  
• DryLab^® allows your company to choose and prioritise the most important factors (cost-efficiency, fast runtime, high robustness, maximum resolution, minimal use of eluents, etc.) instead of leaving it up to coincidence, trial and error results, or to methods, which were validated long time ago.
  
  
• DryLab^® helps you to minimize the abrasion of expensive equipment, such as columns eluents and seals. It increases the overall robustness of your chromatographic work.
  
  
• DryLab^® makes the teaching of specifications of methods in HPLC/GC to an easy, cheap, and fast undertaking.

With a minimum of experimental effort, DryLab^® supports you with the maximum of information on your method. Without ever loosing control, DryLab^® turns chromatography into a playful and fun experience:


→ Model All Relevant Variables for LC or GC Separations!

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Question: "I work with difficult samples ... will DryLab^® help me?"
Answer: DryLab^® includes LC modelling options for gradient conditions, isocratic %B, pH, ternary mobile phases, ionic strength, additive/buffer concentration, normal phase, temperature, reversed-phase gradient/temperature, as well as temperature program for GC separations. In addition, DryLab^®s Column Optimization option lets you model changes in column dimensions, particle size, and flow rate. Dwell volume changes and peak tailing can also be modelled to simplify method transfer.


→ Use the 3-D Resolution Map to Model Two Separation Variables Simultaneously!

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Question: "Can I model more than one variable at a time?"
Answer: DryLab^®s 3-D Resolution Map predicts the best mobile phase conditions for modes that model two variables simultaneously. Modeling gradient conditions and temperature, for example, provides excellent selectivity control for complex samples.


→ Find the Best Conditions for ANY Component in a Complex Mixture!

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Problem: "I am only interested in one degradation product in a complex mixture."
Solution: DryLab^®s Resolution Map shows how resolution changes with separation conditions - for one peak, for several peaks, or for all peaks under evaluation.


→ Troubleshooting Existing Methods!

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Question: "Will a change in separation conditions make my method work again?"
Answer: DryLab^® tells you at a glance by modeling and comparing a separation under a variety of conditions.


→ Teach New Chromatographers!
Training new staff is time-consuming, and mistakes made at the instrument can be costly. DryLab^® let’s novices do their learning on the computer. As they alter experimental conditions, DryLab^® provides immediate feedback. And, DryLab^® comes with a Tutorial Guide and built-in examples for self-instruction.


→ Shorten Run Times!
Problem: "I need to shorten my run time to get more samples done each day."
Solution: DryLab^® lets you try out different column configuration and flow rates in seconds.


→ Evaluate Method Robustness!

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Question: "How senstitive is my method to small inaccuracies in conditions?"
Answer: The Robust Resolution Map shows you EXACTLY how rugged your method is. Identify the best conditions to avoid reproducibility problems.


→ Import Your Data Files!
DryLab^® imports data files from nearly any chromatography data system or allows you to customize an import template.


→ Account for Peak Tailing in Your Modeling!

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Problem: "My separations almost always have tailing peaks."
Solution: DryLab^® models peak tailing to give you a realistic prediction of what your separation will look like when you run your DryLab^® conditions in the laboratory.


→ Transfer Gradient Methods from One Instrument to Another!

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Problem: "I need to standardize gradient methods for a variety of instruments in our lab."
Solution: DryLab^®s Gradient Editor predicts the optimum linear gradient for your separation and lets you model multisegmented gradients or adjust methods for different instrument configurations. For example, you can adjust the method for an other instrument with a different dwell volume.